Chromatographic Separation Studies of Cephalosporins on CTAB Modified Silica Layers with Different Buffer Solvent Systems
نویسنده
چکیده
Various surfactant modified silica layers were used for the chromatography of five different Cephalosporins. The 4% methanolic CTAB impregnated silica layer was useful for the chromatography of Cephalosporins. The acidic buffer solvent systems were used with the 4% methanolic CTAB impregnated silica layers for the separation of different mixtures [A (Cefaclor, Ceftriaxone and Cefadroxil), B (Ceftriaxone, Cefoprazone and Cephalexin) and C (Cefaclor, Ceftriaxone and Cephalexin)] of Cephalosporins. The interference due to the presence of sodium and potassium salts, glucose and urea on the identification and mobility of all the five Cephalosporins were also examined.
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